Fallypride precursor

Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497) . Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with 18F[1].

Product Specifications

CAS Number

[166173-74-6]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fallypride-precursor.html

Purity

98.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CCN(CCC1)[C@@H]1CNC(C2=C(C(OC)=CC(CCCOS(=O)(C3=CC=C(C=C3)C)=O)=C2)OC)=O

Molecular Formula

C27H36N2O6S

Molecular Weight

516.65

References & Citations

[1]Mukherjee J, et al., Fluorinated benzamide neuroleptics--III. Development of (S) -N-[ (1-allyl-2-pyrrolidinyl) methyl]-5- (3-[18F]fluoropropyl) -2, 3-dimethoxybenzamide as an improved dopamine D-2 receptor tracer. Nucl Med Biol. 1995 Apr;22 (3) :283-96.