Benzoin

Benzoin (DL-Benzoin), a natural balsamic resin, is a PI3Kα inhibitor with anticancer effects. Benzoin inihits the growth of colon cancer cell line (HCT-116) . Benzoin can be used as a food additive[1][2].

Product Specifications

CAS Number

[119-53-9]

Product Name Alternative

DL-Benzoin; Desyl alcohol; (±) -2-Hydroxy-2-phenylacetophenone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PI3K

Type

Natural Products

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/benzoin.html

Purity

99.95

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C1=CC=CC=C1)C(C2=CC=CC=C2)=O

Molecular Formula

C14H12O2

Molecular Weight

212.25

Precautions

H302, H315, H319, H335

References & Citations

[1]John JW Coppen, et al. Benzoin: Production, Uses and International Trade. Apr 6th, 2016.|[2]Sabbah DA, et al. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα) . Bioorg Med Chem Lett. 2015 Aug 15;25 (16) :3120-4.