Isonipecotic acid
Product Specifications
UNSPSC Description
Isonipecotic acid is a GABAA receptor partial agonist[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isonipecotic-acid.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C1CCNCC1)O
Molecular Weight
129.159
References & Citations
[1]Krehan D, et al. Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective GABA(C) receptor antagonists. Neurochem Int. 2003 Jun;42(7):561-5. |[2]Falch E, et al. GABA-mimetic activity and effects on diazepam binding of aminosulphonic acids structurally related to piperidine-4-sulphonic acid. J Neurochem. 1985 Jan;44(1):68-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-Y1176/Isonipecotic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Y1176/Isonipecotic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
498-94-2
Available Sizes
Curated Selection
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