BTK ligand 11
Product Specifications
UNSPSC Description
BTK ligand 11 is a PROTAC target protein ligand that can be used to synthesize BCPyr (HY-142621)[1].
Target Antigen
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/btk-ligand-11.html
Smiles
FC1=CC=C(OC2=CC=C(C3=NN([C@H]4CN(C(O)=O)CCC4)C(N)=C3C(N)=O)C=C2)C(F)=C1
Molecular Weight
457.43
References & Citations
[1]James Schiemer, et al. Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes. Nat Chem Biol. 2021 Feb;17(2):152-160.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168314/BTK-ligand-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168314/
Clinical Information
No Development Reported
Curated Selection
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