Dehydrodanshenol A
Product Specifications
UNSPSC Description
Dehydrodanshenol A is a non-competitive inhibitor of Protein tyrosine phosphatase 1B (PTP1B), with an IC50 value of 8.5 μM. Dehydrodanshenol A can be used in diabetes-related research[1].
Target Antigen
Phosphatase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dehydrodanshenol-a.html
Solubility
10 mM in DMSO
Smiles
CC(C[C@@]1(C2=C(C=CC=C3C)C3=CC=C2C4=C(C(C)=CO4)C1=O)O)=O
Molecular Weight
334.37
References & Citations
[1]Kim DH, et al. Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem Biol Interact. 2017 Dec 25;278:65-73.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N12736/Dehydrodanshenol-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N12736/
Clinical Information
No Development Reported
CAS Number
1444618-61-4
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