PLCD3 rabbit pAb
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca (2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q8N3E9
Swiss Prot
Q8N3E9
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human PLCD3 AA range: 501-551
Target
PLCD3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow . Localizes at the cleavage furrow during cytokinesis. .
Gene ID (Human)
113026
Available Sizes
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