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POSTN Polyclonal Antibody

Product Specifications

Background

Periostin (POSTN, PN), originally named as osteoblast-specific factor 2 (OSF-2), is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues, and has a role in bone, tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types, includidng lung, ovary, breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour, and it is required to allow cancer stem cell maintenance.

Abbreviation

POSTN

UniProt

Q15063

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human POSTN protein expressed by E.coli

Target

Fasciclin-I like; MGC119510; MGC119511; OSF 2; OSF-2; OSF2; Osteoblast specific factor 2 (fasciclin I like) ; Osteoblast specific factor 2; Osteoblast specific factor; Osteoblast-specific factor 2; PDLPOSTN; Periodontal ligament specific periostin; Periostin; Periostin isoform thy2; Periostin isoform thy4; Periostin isoform thy6; Periostin isoform thy8; Periostin osteoblast specific factor; PN; POSTN; POSTN; RP11 412K4.1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Signal Transduction; Tags and Cell Markers

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

IHC 1:100-1:200

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG

Available Sizes

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