MANS peptide
Product Specifications
UNSPSC Description
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis[1].
Target Antigen
MARCKS; PKC
Type
Peptides
Related Pathways
Cytoskeleton;Epigenetics;TGF-beta/Smad
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mans-peptide.html
Solubility
10 mM in DMSO
Smiles
C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(CNC(CCCCCCCCCCCCC)=O)=O)C)=O)CCC(N)=O)=O)=O)CO)=O)CCCCN)=O)[C@@H](C)O)=O)C)=O)C)=O)CCCCN)=O)=O)CCC(O)=O)=O)C)=O)C)=O)C)=O)CCC(O)=O)=O)CCCNC(=N)N)(=O)N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C(C)C)=O)C)=O)C)=O)CCC(O)=O)=O)=O)CCC2
Molecular Weight
2498.83
References & Citations
[1]Chen CH, et al., A peptide that inhibits function of Myristoylated Alanine-Rich C Kinase Substrate (MARCKS) reduces lung cancer metastasis. Oncogene. 2014 Jul 10;33(28):3696-706.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10218/MANS-peptide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10218/
Clinical Information
No Development Reported
CAS Number
479482-23-0
Curated Selection
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