MitoPQ

MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1].

Product Specifications

CAS Number

[1821370-28-8]

Product Name Alternative

MitoParaquat

UNSPSC

12352005

Hazard Statement

H301, H311, H331

Target

ROS Kinase

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mitopq.html

Purity

99.91

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]

Molecular Formula

C39H46I3N2P

Molecular Weight

954.48

Precautions

H301, H311, H331

References & Citations

[1]Robb EL, et al. Selective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat. Free Radic Biol Med. 2015 Dec;89:883-94.