Cearoin
Cearoin increases autophagy and apoptosis through the production of ROS and the activation of ERK[1].
Product Specifications
CAS Number
[52811-37-7]
UNSPSC
12352005
Target
Apoptosis; Autophagy; ERK; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cearoin.html
Purity
99.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(O)=C(OC)C=C1O)C2=CC=CC=C2
Molecular Formula
C14H12O4
Molecular Weight
244.24
References & Citations
[1]Tonking Bastola, et al. Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells. Molecules. 2017 Feb 6;22 (2) :242.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERK
Curated Selection
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