Triptonodiol

Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2].

Product Specifications

CAS Number

[117456-87-8]

UNSPSC

12352005

Target

GSK-3

Type

Natural Products

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/triptonodiol.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C1[C@](C)(CO)[C@]2([H])CCC3=C(C(O)=CC(C(C)C)=C3OC)[C@@]2(C)CC1

Molecular Formula

C21H30O4

Molecular Weight

346.46

References & Citations

[1]Zhou BN, et al. Studies on New Components and Stereochemistry of Diterpenoids from Trypterygium wilfordii. Planta Med. 1988 Aug;54 (4) :330-2. |[2]Feng Jin, et al. Network pharmacology‑based investigation of potential targets of Triptonodiol acting on Non-Small-Cell Lung Cancer. Research Square. 2023. DOI: 10.21203/rs.3.rs-2463976/v1