KPH2f
KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM) [1].
Product Specifications
CAS Number
[2760615-09-4]
UNSPSC
12352005
Target
GLUT; URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kph2f.html
Purity
99.22
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
N#CC1=C2C=CC=CC2=C(C=C1)NC3=C(C=CN=C3)SCC4=CC=CC=C4C(O[Na])=O
Molecular Formula
C24H16N3NaO2S
Molecular Weight
433.46
References & Citations
[1]Zhao Z, et al. Discovery of novel verinurad analogs as dual inhibitors of URAT1 and GLUT9 with improved Druggability for the treatment of hyperuricemia. Eur J Med Chem. 2022;229:114092.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1407080-01 0.02 mg (E-Coli)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details 
MBS1407080-02 0.1 mg (E-Coli)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details MBS1407080-03 0.02 mg (Yeast)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details MBS1407080-04 0.1 mg (Yeast)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details 
MBS1407080-05 0.02 mg (Baculovirus)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details MBS1407080-06 0.02 mg (Mammalian-Cell)
Recombinant Burkholderia sp. Kynurenine formamidase (kynB)
Ask
View Details