Neuromedin U-25 (human)
Product Specifications
UNSPSC Description
Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds[1][2].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/neuromedin-u-25-human.html
Solubility
10 mM in DMSO
Smiles
C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CCCNC(=N)N)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)CO)=O)CCC4)CC7=CC=CC=C7)=O)C)=O)CO)=O)CCC(N)=O)=O)CO)=O)CCCNC(=N)N)=O)=O)=O)=O)CC(C)C)=O)=O)CCCNC(=N)N)(=O)N8[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CCCNC(=N)N)=O)CCC8
Molecular Weight
3080.37
References & Citations
[1]Mitchell JD, et al., Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system. Cardiovasc Res. 2009 Feb 1;81(2):353-61. |[2]Alfa RW, et al., Suppression of insulin production and secretion by a decretin hormone. Cell Metab. 2015 Feb 3;21(2):323-334.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2378/Neuromedin-U-25-human-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2378/
Clinical Information
No Development Reported
CAS Number
312306-89-1
Curated Selection
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