Radioprotectin-1

Radioprotectin-1 is a potent and specific nonlipid agonist of lysophosphatidic acid receptor 2 (LPA2), with an EC50 value of 25 nM for murine LPA2 subtype[1].

Product Specifications

CAS Number

[1622006-09-0]

Product Name Alternative

OPC-14857-d8; DM-14857-d16

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/radioprotectin-1.html

Purity

99.49

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC(Cl)=CC=C1S(=O)(NCCCCN(C(C2=CC=CC3=CC=CC4=C23)=O)C4=O)=O

Molecular Formula

C23H19ClN2O6S

Molecular Weight

486.92

Precautions

H302, H315, H319, H335

References & Citations

[1]Kuo B, et al. The LPA2 receptor agonist Radioprotectin-1 spares Lgr5-positive intestinal stem cells from radiation injury in murine enteroids. Cell Signal. 2018 Nov;51:23-33.