ALDH1A3-IN-2
Product Specifications
UNSPSC Description
ALDH1A3-IN-2 (Compound 15) is a potent inhibitor of ALDH1A3 with an IC50 of 1.29 μM. Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer. ALDH1A3-IN-2 has the potential for the research of cancer diseases[1].
Target Antigen
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aldh1a3-in-2.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=CC1=CC(C)=C(C=C1)N2CCCCC2
Molecular Weight
203.28
References & Citations
[1]Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144669/ALDH1A3-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144669/ALDH1A3-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
886502-08-5
Available Sizes
Curated Selection
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