ERP27, Human (HEK293, His)

The ERP27 protein has a unique role in that it can specifically bind unfolded proteins and recruit the protein disulfide isomerase PDIA3 to the substrate through the hydrophobic pocket in its C-terminal domain. This interaction implies that ERP27 is involved in the unfolding stress response and resolves challenges in cellular proteostasis. ERP27 Protein, Human (HEK293, His) is the recombinant human-derived ERP27 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ERP27 Protein, Human (HEK293, His) is 248 a.a., with molecular weight of 32-38 kDa.

EVEKSSDGPG AAQEPTWLTD VPAAMEFIAA TEVAVIGFFQ DLEIPAVPIL HSMVQKFPGV SFGISTDSEV LTHYNITGNT ICLFRLVDNE QLNLEDEDIE SIDATKLSRF IEINSLHMVT EYNPVTVIGL FNSVIQIHLL LIMNKASPEY EENMHRYQKA AKLFQGKILF ILVDSGMKEN GKVISFFKLK ESQLPALAIY QTLDDEWDTL PTAEVSVEHV QNFCDGFLSG KLLKENRESE GKTPKVEL