L-selectin/CD62L, Mouse (294a.a, HEK293, C-Fc-His)

L-selectin, a calcium-dependent lectin, binds to glycoproteins on adjacent cells, facilitating lymphocyte attachment to endothelial cells in peripheral lymph nodes.This interaction is essential for leukocyte rolling along the endothelium and requires L-selectin's binding to SELPLG/PSGL1 and PODXL2, dependent on glycan and sulfation modifications.Sulfation of 'Tyr-51' on SELPLG is particularly important for L-selectin binding.L-selectin/CD62L Protein, Mouse (HEK293, C-Fc-His) is the recombinant mouse-derived L-selectin/CD62L protein, expressed by HEK293 , with C-6*His, C-Fc labeled tag.

WTYHYSEKPM NWENARKFCK QNYTDLVAIQ NKREIEYLEN TLPKSPYYYW IGIRKIGKMW TWVGTNKTLT KEAENWGAGE PNNKKSKEDC VEIYIKRERD SGKWNDDACH KRKAALCYTA SCQPGSCNGR GECVETINNH TCICDAGYYG PQCQYVVQCE PLEAPELGTM DCIHPLGNFS FQSKCAFNCS EGRELLGTAE TQCGASGNWS SPEPICQVVQ CEPLEAPELG TMDCIHPLGN FSFQSKCAFN CSEGRELLGT AETQCGASGN WSSPEPICQE TNRSFSKIKE GDYN