Dehydroemetine

Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis[1][2][3].

Product Specifications

CAS Number

[4914-30-1]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dehydroemetine.html

Purity

99.90

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

COC1=CC2=C(C=C1OC)CCN[C@@H]2CC3=C(CC)CN4CCC5=CC(OC)=C(OC)C=C5[C@]4([H])C3

Molecular Formula

C29H38N2O4

Molecular Weight

478.62

References & Citations

[1]Fouarge M, et al.Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis.J Microencapsul. 1989 Jan-Mar;6 (1) :29-34.|[2]Salako LA. Pharmacodynamic effects of dehydroemetine. J Pharm Pharmacol. 1972 Jan;24 (1) :32-9.|[3]SALEM HH, et al. DEHYDROEMETINE IN ACUTE AMOEBIASIS. Trans R Soc Trop Med Hyg. 1964 Nov;58:539-44.