PROTAC erf3a Degrader-1
Product Specifications
UNSPSC Description
PROTAC erf3a Degrader-1 (Compound C63) is an orally active PROTAC erf3a Degrader. PROTAC erf3a Degrader-1 inhibits cancer cell proliferation (eg: 22Rv1). PROTAC erf3a Degrader-1 can be used for research of prostate cancer, ovarian cancer, liver cancer, cervical cancer, leukemia, breast cancer. (Red: erf3a ligand (HY-13778); Black: linker (HY-163960); Blue: CRBN ligand (HY-41547))[1].
Target Antigen
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-erf3a-degrader-1.html
Smiles
O=C(N1[C@@H]2C(NC(CC2)=O)=O)C3=CC=CC(N[C@H](CCC4)C[C@@H]4NC5=CC(NC([C@H]6CC[C@]([C@@]7([H])[C@@](CC8)([H])[C@@]9([C@@](NC(C=C9)=O)([H])CC7)C)([H])[C@]86C)=O)=CC=C5)=C3C1=O
Molecular Weight
760.92
References & Citations
[1]Guangliang Yu, et al. Medicine for treating human tumor by eRF3a targeting protein degradation mechanism. Patent. CN117801051A.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163938/PROTAC-erf3a-Degrader-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163938/
Clinical Information
No Development Reported
CAS Number
3033871-19-8
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