Penconazole

Penconazole is a typical triazole fungicide, and mainly applied on apples, grapes, and vegetables to control powdery mildew. Penconazole inhibits sterol biosynthesis in fungi. Penconazole decrease AChE activity in the cerebrum and cerebellum of rats[1][2].

Product Specifications

CAS Number

[66246-88-6]

UNSPSC

12352005

Hazard Statement

H302, H361, H400, H410

Target

Cholinesterase (ChE) ; Fungal

Type

Reference compound

Related Pathways

Anti-infection; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/penconazole.html

Concentration

10mM

Purity

98.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCC(C1=CC=C(Cl)C=C1Cl)CN2N=CN=C2

Molecular Formula

C13H15Cl2N3

Molecular Weight

284.18

Precautions

H302, H361, H400, H410

References & Citations

[1]Husak VV, et al. Acute exposure to the penconazole-containing fungicide Topas partially augments antioxidant potential in goldfish tissues. Comp Biochem Physiol C Toxicol Pharmacol. 2017;193:1-8.|[2]Chaâbane M, et al. Penconazole alters redox status, cholinergic function, and membrane-bound ATPases in the cerebrum and cerebellum of adult rats. Hum Exp Toxicol. 2017;36 (8) :854-866.