CAY10464

CAY10464 (AHR antagonist 7; compound 4j) is a selective and high-affinity aryl hydrocarbon receptor (AhR) antagonist with a Ki of 1.4 nM[1].

Product Specifications

CAS Number

[688348-37-0]

Product Name Alternative

AHR antagonist 7

UNSPSC

12352005

Target

Aryl Hydrocarbon Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cay10464.html

Purity

99.77

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=CC(Cl)=CC(/C=C/C2=CC=C(OC)C=C2)=C1

Molecular Formula

C15H12Cl2O

Molecular Weight

279.16

References & Citations

[1]Emad Naem, et al. Inhibition of apolipoprotein A-I gene by the aryl hydrocarbon receptor: a potential mechanism for smoking-associated hypoalphalipoproteinemia. Life Sci. 2012 Jul 26;91 (1-2) :64-9. |[2]Philippe de Medina, et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem. 2005 Jan 13;48 (1) :287-91.