Trihydroxycholestanoic acid

Trihydroxycholestanoic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Refsum Disease, D Bifunctional Protein Deficiency and Infantile Refsum Disease[1][2][3][4].

Product Specifications

CAS Number

[547-98-8]

Product Name Alternative

Coprocholic acid

UNSPSC

12352211

Hazard Statement

H302

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/trihydroxycholestanoic-acid.html

Concentration

10mM

Purity

99.48

Solubility

10 mM in DMSO

Smiles

CC(C(O)=O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C

Molecular Formula

C27H46O5

Molecular Weight

450.65

Precautions

H302

References & Citations

[1]Baumgartner MR, et al. Clinical approach to inherited peroxisomal disorders: a series of 27 patients. Ann Neurol. 1998 Nov;44 (5) :720-30. |[2]Poll-The BT, et al. Infantile Refsum's disease: biochemical findings suggesting multiple peroxisomal dysfunction. J Inherit Metab Dis. 1986;9 (2) :169-74.|[3]Rizzo C, et al. Characteristic acylcarnitine profiles in inherited defects of peroxisome biogenesis: a novel tool for screening diagnosis using tandem mass spectrometry. Pediatr Res. 2003 Jun;53 (6) :1013-8. |[4]Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39 (35) :5709-5720.