Cy5-PEG3-azide

Cy5-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Cy5-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cy5-peg3-azide.html

Purity

99.47

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)C(C=CC=C4)=C4C3(C)C.[Cl-]

Molecular Formula

C40H55ClN6O4

Molecular Weight

719.36

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562