α-Pyridone

α-Pyridone (2-Pyridone) is an antibacterial agent. α-Pyridone can be synthesized via the 1,4-addition of 2- (phenylsulfinyl) acetamide to α, β-unsaturated ketones followed by cyclization and sulfoxide elimination. α-Pyridone can also be used to synthesize a wide range of heterocyclic compounds[1][2].

Product Specifications

CAS Number

[142-08-5]

Product Name Alternative

2-Pyridone

UNSPSC

12352005

Hazard Statement

H301

Target

Bacterial; Endogenous Metabolite

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/alpha-pyridone.html

Purity

99.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=CC=CN1

Molecular Formula

C5H5NO

Molecular Weight

95.10

Precautions

H301

References & Citations

[1]Masaya Fujii, et al., 2-Pyridone Synthesis Using 2- (Phenylsulfinyl) acetamide. Org. Lett. 2013, 15, 1, 232–234. |[2]Mostafa M.K. Amer, et al., Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds. Journal of Saudi Chemical Society, 2021.