Syk (phospho-Ser297) rabbit pAb
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Product Specifications
Background
Synonyms
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene ID
6850
UniProt
P43405
Cellular Locus
Cell membrane. Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human Syk (Ser297)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
72kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12864-1.pdf
Observed Molecular Weight
72 kD
Subcellular Location
Cell membrane . Cytoplasm, cytosol .
Other Product Names
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene ID (Human)
6850
SwissProt (Human)
P43405
Available Sizes
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