Maresin 1

Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity[1][2][3].

Product Specifications

CAS Number

[1268720-28-0]

Product Name Alternative

CC 122

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/maresin-1.html

Concentration

277.4 μM * 250 μL in Ethanol

Purity

99.00

Solubility

10 mM in DMSO

Smiles

CC/C=C\C/C=C\C[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\CCC(O)=O

Molecular Formula

C22H32O4

Molecular Weight

360.49

Precautions

H302, H315, H319, H335

References & Citations

[1]Markus V Olsen, et al. Maresin 1, a Specialized Proresolving Mediator, Stimulates Intracellular [Ca 2+ ] and Secretion in Conjunctival Goblet Cells. J Cell Physiol. 2020 Jun 8.|[2]Macrophage Proresolving Mediator Maresin 1 Stimulates Tissue Regeneration and Controls Pain|[3]Rodrigo Marcon, et al. Maresin 1, a Proresolving Lipid Mediator Derived From omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis. J Immunol. 2013 Oct 15;191 (8) :4288-98.