Dimercaprol

Dimercaprol (2,3-Dimercapto-1-propanol) is an anti-heavy metal-poisoning agent, which exhibits anti-HIV activity. Dimercaprol can be used for the study for arsenic, mercury, gold, lead, antimony, and other toxic metal poisoning[1].

Product Specifications

CAS Number

[59-52-9]

Product Name Alternative

2,3-Dimercapto-1-propanol; Dithioglycerol

UNSPSC

12352100

Hazard Statement

H301, H315, H319, H335

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dimercaprol.html

Purity

99.0

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 16.67 mg/mL (ultrasonic)

Smiles

OCC(S)CS

Molecular Formula

C3H8OS2

Molecular Weight

124.23

Precautions

H301, H315, H319, H335

References & Citations

[1]Kubota S, et al. 2,3 Dimercapto-1-propanol inhibits HIV-1 tat activity, viral production, and infectivity in vitro. AIDS Res Hum Retroviruses. 1990 Jul;6 (7) :919-27.|[2]Ran Tian, et al. Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury. J Neurochem. 2017 Jun;141 (5) :708-720. |[3]Taciane Roza, et al. 2,3-Dimercapto-1-propanol does not alter the porphobilinogen synthase inhibition but decreases the mercury content in liver and kidney of suckling rats exposed to HgCl2. Basic Clin Pharmacol Toxicol. 2005 Apr;96 (4) :302-8.