Sulcatone

Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis[1][2][3][4].

Product Specifications

CAS Number

[110-93-0]

Product Name Alternative

6-Methyl-5-hepten-2-one

UNSPSC

12352211

Hazard Statement

H226, H412

Target

Adenosine Receptor; Cytochrome P450; Endogenous Metabolite; Fungal; Parasite

Type

Natural Products

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sulcatone.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(CC/C=C(C)\C)=O

Molecular Formula

C8H14O

Molecular Weight

126.20

Precautions

H226, H412

References & Citations

[1]Achimón F, et al. Sulcatone as a Plant-Derived Volatile Organic Compound for the Control of the Maize Weevil and Its Associated Phytopathogenic Fungi in Stored Maize. Plants (Basel) . 2024 Oct 16;13 (20) :2893.|[2]Green, et al. P76 Faecal sulcatone: a new marker of disease activity in ulcerative colitis (UC) ?. 2023. A88-A89.|[3]Gonzalez Audino P, et al. Identification of volatile emissions from Platypus mutatus (=sulcatus) (Coleoptera: Platypodidae) and their behavioral activity. J Econ Entomol. 2005 Oct;98 (5) :1506-9.|[4]SANTOS, et al. AVALIAÇÃO CITOTÓXICA EM CÉLULAS A7r5 E ANTI-HIPERTENSIVA EM RATOS SHR INDUZIDO PELA 6-METIL-5-HEPTEN-2-ONA (SULCATONA) . Diss. 2022.