β-Cedrene

β-Cedrene ((+) -β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM[1][2].

Product Specifications

CAS Number

[546-28-1]

Product Name Alternative

(+) -β-Cedrene

UNSPSC

12352211

Hazard Statement

H410

Target

Fungal

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/β-cedrene.html

Solubility

10 mM in DMSO

Smiles

C[C@H]1[C@@]23[C@](CC1)([H])C(C)([C@@](C(CC3)=C)([H])C2)C

Molecular Formula

C15H24

Molecular Weight

204.35

Precautions

P273-P391-P501

References & Citations

[1]Ertugrul K, et al. Essential oils from flowers of Centaurea kotschyi var. kotschyi and C. kotschyi var. decumbens from Turkey[J]. Flavour and fragrance journal, 2003, 18 (2) : 95-97.|[2]Jeong H U, et al. Inhibitory effects of cedrol, β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes[J]. Journal of Toxicology and Environmental Health, Part A, 2014, 77 (22-24) : 1522-1532.