JQ-1 carboxylic acid-PEG3-C2-NH2
Product Specifications
UNSPSC Description
JQ-1 carboxylic acid-PEG3-C2-NH2 is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jq-1-carboxylic-acid-peg3-c2-nh2.html
Smiles
NCCOCCOCCOCCNC(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=C(SC(C)=C3C)N4C(C)=NN=C14)=O
Molecular Weight
575.12
References & Citations
[1]Tao Y, et, al. Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1. J Am Chem Soc. 2022 Oct 12;144(40):18688-18699.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169150/JQ-1-carboxylic-acid-PEG3-C2-NH2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169150/
Clinical Information
No Development Reported
CAS Number
2098790-24-8
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