BF-1
Product Specifications
UNSPSC Description
BF-1 is a 5-HT2B receptor antagonist with a pKi value of 10.05 and an IC50 value of 2.6 nM[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bf-1.html
Smiles
CN1CC/C(CC1)=C2C3=C(SC4=C\2C=CC(OCC)=C4)C=CC=C3OC
Molecular Weight
367.50
References & Citations
[1]Beate Schmitz, et al. BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs. Eur J Pharmacol. 2015 Mar 15:751:73-80.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119946/BF-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119946/
Clinical Information
Phase 1
CAS Number
518980-66-0
Curated Selection
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