Methionine

Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation.

Product Specifications

CAS Number

[348-67-4]

Product Name Alternative

MRX-1024; D-Methionine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/MRX-1024.html

Concentration

10mM

Purity

99.86

Solubility

H2O : 25 mg/mL (ultrasonic)

Smiles

N[C@H](CCSC)C(O)=O

Molecular Formula

C5H11NO2S

Molecular Weight

149.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Wu C, et al. Antioxidants L-carnitine and D-methionine modulate neuronal activity through GABAergic inhibition. J Neural Transm (Vienna) . 2014 Jul;121 (7) :683-93.|[2]Sooriyaarachchi M, et al. Chemoprotection by D-methionine against cisplatin-induced side-effects: insight from in vitrostudies using human plasma. Metallomics. 2014 Mar;6 (3) :532-41.|[3]Hinduja S, et al. D-methionine protects against cisplatin-induced neurotoxicity in the hippocampus of the adult rat. Neurotox Res. 2015 Apr;27 (3) :199-204.