Permethrin-d5

Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

Product Specifications

CAS Number

[1794760-19-2]

Product Name Alternative

NRDC-143-d5

UNSPSC

12352005

Hazard Statement

H302+H332-H317-H410

Target

Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

99.21

Solubility

10 mM in DMSO|DMSO : 50mg/mL (ultrasonic)

Smiles

C(=C(Cl)Cl)C1C(C(OCC2=CC(OC3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H])=CC=C2)=O)C1(C)C

Molecular Formula

C21H15D5Cl2O3

Molecular Weight

396.32

Precautions

P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Xiao X, et al. Exposure to permethrin promotes high fat diet-induced weight gain and insulin resistance in male C57BL/6J mice. Food Chem Toxicol. 2018 Jan;111:405-416.|[3]Smith LB, et al. CYP-mediated permethrin resistance in Aedes aegypti and evidence for trans-regulation. PLoS Negl Trop Dis. 2018 Nov 19;12 (11) :e0006933.