2,3-Pentanedione

2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans[1].

Product Specifications

CAS Number

[600-14-6]

UNSPSC

12352211

Hazard Statement

H225, H317, H373, H402

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2-3-pentanedione.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C(CC)=O)=O

Molecular Formula

C5H8O2

Molecular Weight

100.12

Precautions

H225, H317, H373, H402

References & Citations

[1]Morgan DL, et al. Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. Toxicol Pathol. 2012;40 (3) :448-465.|[2]Das S, et al., Small molecule diketone flavorants diacetyl and 2,3-pentanedione promote neurotoxicity but inhibit amyloid β aggregation. Toxicol Lett. 2019 Jan;300:67-72.|[3]Hubbs AF, et al., Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats. Am J Pathol. 2012 Sep;181 (3) :829-44.