Prostaglandin E2

Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

Product Specifications

CAS Number

[363-24-6]

Product Name Alternative

PGE2; Dinoprostone

UNSPSC

12352211

Hazard Statement

H302, H360

Target

Endogenous Metabolite; Organoid; Prostaglandin Receptor

Type

Natural Products

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Prostaglandin_E2.html

Purity

99.90

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O

Molecular Formula

C20H32O5

Molecular Weight

352.47

Precautions

H302, H360

References & Citations

[1]Chouaib S, et al. The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol. 1984 Apr;132 (4) :1851-7.|[2]Fernandez-Repollet E, et al. In vivo effects of prostaglandin E2 and arachidonic acid on phagocytosis of fluorescent methacrylate microbeads by rat peritoneal macrophages. J Histochem Cytochem. 1982 May;30 (5) :466-70.|[3]Haylor J, et al. Renal vasodilator activity of prostaglandin E2 in the rat anaesthetized with pentobarbitone. Br J Pharmacol. 1982 May;76 (1) :131-7.