Isoconazole (nitrate)

Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential[1].

Product Specifications

CAS Number

[24168-96-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Antibiotic; Bacterial; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Isoconazole-nitrate.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(COC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C(Cl)=CC=C1.O[N+]([O-])=O

Molecular Formula

C18H15Cl4N3O4

Molecular Weight

479.14

Precautions

H302, H315, H319

References & Citations

[1]Veraldi S, et al. Isoconazole nitrate: a unique broad-spectrum antimicrobial azole effective in the treatment of dermatomycoses, both as monotherapy and in combination with corticosteroids. Mycoses. 2013 May;56 Suppl 1:3-15.|[2]Gugnani HC, et al. Isoconazole nitrate in the treatment of tropical dermatomycoses. Mycoses. 1994 Jan-Feb;37 (1-2) :39-41.