OADS
Product Specifications
UNSPSC Description
OADS is a Chloride channel antiporter (ClC-ec1) inhibitor (IC50: 29 μM). OADS specifically inhibits the ClC-ec1 antiporter but not the ClC-1 channel. OADS can be used for research of osteoporosis and neurodegenerative and cardiovascular diseases[1].
Target Antigen
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/oads.html
Smiles
O=S(C1=CC(NC(CCCCCCC)=O)=CC=C1/C=C/C2=CC=C(NC(CCCCCCC)=O)C=C2S(=O)(O)=O)(O)=O
Molecular Weight
622.79
References & Citations
[1]Howery AE, et al. A designed inhibitor of a CLC antiporter blocks function through a unique binding mode. Chem Biol. 2012 Nov 21;19(11):1460-70.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122732/OADS-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122732/
Clinical Information
Phase 4
CAS Number
5970-15-0
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