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UNC8732 (TFA)

Product Specifications

UNSPSC Description

UNC8732 (TFA) is a NSD2 inhibitor and degrader[1].

Target Antigen

Molecular Glues

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/unc8732-tfa.html

Smiles

O=C(C(F)(F)F)O.O=C(C1=CC=C(CN(C2CC2)C(C3=CC=C4NC(COC4=C3)=O)=O)C=C1)NC5=CC=C6C(CCN(C6)C(CCCCCN)=O)=C5

Molecular Weight

723.74

References & Citations

[1]David Y Nie, et al. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Dec;20(12):1597-1607.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-161796A/UNC8732-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-161796A/

Clinical Information

No Development Reported

CAS Number

2929304-06-1

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