CSF1R-IN-12
CSF1R-IN-12 (compound 1) is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-12 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
[2361556-35-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-12.html
Concentration
10mM
Purity
98.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC(NCC2=CN=C(C=C2)C(F)(F)F)=NC=C1C3=CC=CC4=C3CNC4=O
Molecular Formula
C21H17F3N4O
Molecular Weight
398.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Wenyun Qian, et al. Isoindolinone and derivative thereof as csf-1r inhibitor. Patent WO2019134661A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
VDAC1 (Voltage-Dependent anion Channel 1, MGC111064, PORIN, PORIN-31-HL) (HRP)
ARSA (Arylsulfatase A, ASA, Cerebroside-sulfatase, Arylsulfatase A Component B, Arylsulfatase A Component C) (HRP)
