Octyl-α-hydroxyglutarate
Octyl-α-hydroxyglutarate (octyl-2-HG) increases histone methylation and enhances viability of LMP1-negative NPC cells[1].
Product Specifications
CAS Number
[2097068-39-6]
Product Name Alternative
Octyl-2-HG
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/octyl-α-hydroxyglutarate.html
Smiles
O=C(CCC(C(OCCCCCCCC)=O)O)O
Molecular Formula
C13H24O5
Molecular Weight
260.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wei Xu, et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell. 2011 Jan 18;19 (1) :17-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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