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MK-7845

Product Specifications

UNSPSC Description

MK-7845 is a reversible covalent SARS-CoV-2 3CL protease inhibitor with an IC50 of 8.7 nM[1].

Target Antigen

SARS-CoV

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mk-7845.html

Solubility

10 mM in DMSO

Smiles

CNC(C([C@@H](NC([C@@H]1[C@H]2CCC[C@H]2CN1C([C@H](C(C)(C)C)NC(OC)=O)=O)=O)CCC(F)(F)C)=O)=O

Molecular Weight

516.58

References & Citations

[1]Valerie W Shurtleff, et al. Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic. J Med Chem. 2024 Feb 16.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-157778/MK-7845-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-157778/

Clinical Information

No Development Reported

CAS Number

2952554-69-5

Available Sizes

Curated Selection

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