Epostane
Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC50 of 1.45 nM. Epostane blocks ovulation and pregnancy in rats[1].
Product Specifications
CAS Number
[80471-63-2]
Product Name Alternative
WIN 32729
UNSPSC
12352005
Target
3β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/epostane.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@]5([C@@]4([H])CC[C@@]5(O)C)C)[C@](O3)(C(O)=C(C1)C#N)C
Molecular Formula
C22H31NO3
Molecular Weight
357.49
References & Citations
[1]Snyder BW, et al., Inhibition of ovulation in rats with epostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1984 Jul;176 (3) :238-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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