CMX-521

CMX-521, a nucleoside analog, is a potent inhibitor for RNA-dependant RNA polymerase (RdRp) of norovirus. CMX-521 suppresses murine norovirus (MNV) and human norovirus[1].

Product Specifications

CAS Number

[2077178-99-3]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cmx-521.html

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC(C)=NC(N)=C3C(C(N)=O)=C2)O[C@@H]1CO

Molecular Formula

C13H17N5O5

Molecular Weight

323.30

References & Citations

[1]Oluwakemi Ebenezer, et al. Discovery of Potential Inhibitors for RNA-Dependent RNA Polymerase of Norovirus: Virtual Screening, and Molecular Dynamics. Int J Mol Sci. 2020 Dec 26;22 (1) :171.