Boc-Lys (Ac) -AMC
Boc-Lys (Ac) -AMC is a cell-permeable fluorometric HDAC substrate (Ex/Em = 355 nm/460 nm) [1][2].
Product Specifications
CAS Number
[233691-67-3]
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Fluorescent Dye; HDAC
Type
Dye Reagents
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-lys-ac-amc.html
Purity
99.53
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C(C(O1)=C2)=CC=C2NC([C@H](CCCCNC(C)=O)NC(OC(C)(C)C)=O)=O)=CC1=O
Molecular Formula
C23H31N3O6
Molecular Weight
445.51
Precautions
H302, H315, H319, H335
References & Citations
[1]Reddy DS, et al. Measuring Histone Deacetylase Inhibition in the Brain. Curr Protoc Pharmacol. 2018 Jun;81 (1) :e41.|[2]Ueki N, et al. Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease. Nat Commun. 2013;4:2735.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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