Digoxigenin

Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes[1][3].

Product Specifications

CAS Number

[1672-46-4]

Product Name Alternative

Lanadigenin

UNSPSC

12171500

Hazard Statement

H300+H310+H330

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Digoxigenin.html

Concentration

10mM

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1OCC([C@H]2CC[C@]3(O)[C@]4([H])CC[C@]5([H])C[C@@H](O)CC[C@]5(C)[C@@]4([H])C[C@@H](O)[C@]23C)=C1

Molecular Formula

C23H34O5

Molecular Weight

390.51

Precautions

H300+H310+H330

References & Citations

[1]Luo, Yuhao, et al. Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation. Autophagy vol. 17,12 (2021) : 4083-4101.|[2]Karaś, Kaja, et al. The cardenolides strophanthidin, digoxigenin and dihydroouabain act as activators of the human RORγ/RORγT receptors. Toxicology letters vol. 295 (2018) : 314-324.|[3]Barratt, Kristen S, et al. Production of Digoxigenin-Labeled Riboprobes for In Situ Hybridization Experiments. Current protocols in mouse biology vol. 10,2 (2020) : e74.