Pinusolide
Pinusolide is a known platelet-activating factor (PAF) receptor binding antagonist. Pinusolide not only decreases the proliferation activity of tumor cells but specifically induces apoptosis[1].
Product Specifications
CAS Number
[31685-80-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pinusolide.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1([C@H]2CCC3=CCOC3=O)[C@](CCC2=C)([H])[C@](C)(CCC1)C(OC)=O
Molecular Formula
C21H30O4
Molecular Weight
346.46
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shults EE, et al. Gram-scale synthesis of pinusolide and evaluation of its antileukemic potential. Bioorg Med Chem Lett. 2006;16 (16) :4228-4232.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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