Eldacimibe
Product Specifications
UNSPSC Description
Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) [1].
Target Antigen
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/eldacimibe.html
Solubility
10 mM in DMSO
Smiles
CC(C)(CC1=CC=C(CN(/C(NC2=CC(C(C)(C)C)=C(C(C(C)(C)C)=C2)O)=C3C(OC(C)(OC\3=O)C)=O)CCCCCC)C=C1)C
Molecular Weight
634.89
References & Citations
[1]Chhabria M T, et al. Update on patented cholesterol absorption inhibitors[J]. Expert Opinion on Therapeutic Patents, 2009, 19(8): 1083-1107.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106938/Eldacimibe-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106938/
Clinical Information
Phase 2
CAS Number
141993-70-6
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