DCOIT
DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR) -mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca2+ signaling cascades[1].
Product Specifications
CAS Number
[64359-81-5]
Product Name Alternative
Kathon 930
UNSPSC
12352005
Hazard Statement
H302, H314, H317, H330, H410
Target
GnRH Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/dcoit.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : 133.33 mg/mL (ultrasonic)
Smiles
O=C1N(CCCCCCCC)SC(Cl)=C1Cl
Molecular Formula
C11H17Cl2NOS
Molecular Weight
282.23
Precautions
H302, H314, H317, H330, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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