OptoBI-1
OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing[1].
Product Specifications
CAS Number
[2415272-11-4]
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/optobi-1.html
Purity
98.36
Solubility
DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CCCCC1=CC=C(C=C1)/N=N/C2=CC=C(CCCC(N3CCC(CC3)N4C(NC5=CC=CC=C45)=O)=O)C=C2
Molecular Formula
C32H37N5O2
Molecular Weight
523.67
References & Citations
[1]Oleksandra Tiapko, et al. Lipid-independent control of endothelial and neuronal TRPC3 channels by light. Chem Sci. 2019 Jan 15;10 (9) :2837-2842.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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