Methyllinderone

Methyllinderone is an inhibitor of AP-1/STAT/ERK. Methyllinderone has anti-inflammatory effect. Methyllinderone reduce the invasion and migration rate of TPA-stimulated MCF-7 cells. Methyllinderone can be used in study breast cancer metastasis[1].

Product Specifications

CAS Number

[3984-73-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

AP-1; ERK; STAT

Type

Natural Products

Related Pathways

Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/methyllinderone.html

Solubility

10 mM in DMSO

Smiles

COC(/C=C/C1=CC=CC=C1)=C2C(C(OC)=C(C/2=O)OC)=O

Molecular Formula

C17H16O5

Molecular Weight

300.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yoon JH, et al. Methyl Linderone Suppresses TPA-Stimulated IL-8 and MMP-9 Expression Via the ERK/STAT3 Pathway in MCF-7 Breast Cancer Cells. J Microbiol Biotechnol. 2020 Mar 28;30 (3) :325-332.